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Furthermore, mangiferin markedly inhibits LPS/D-GalN-induced inflammatory factors, including IL-1, TNF-, NLRP3, apoptosis-associated speck-like protein containing a CARD and caspase-1 (102)

Myofibroblast Large agreement identifies in myofibroblasts the professional cells involved in the enhanced ECM deposition occurring during fibrosis development

For example, lapatinib induces ferroptosis via iron-dependent ROS generation in the early stages but promotes protective autophagy to facilitate drug resistance in the later stages [157]